TOP CONOLIDINE ALKALOID FOR CHRONIC PAIN SECRETS

Most a short while ago, it's been identified that conolidine and the above derivatives act over the atypical chemokine receptor 3 (ACKR3. Expressed in similar regions as classical opioid receptors, it binds to a big selection of endogenous opioids. As opposed to most opioid receptors, this receptor acts like a scavenger and doesn't activate a next